MPT0B390 is an arylsulfonamide-based derivative with potent HDAC inhibitory ability. It acts as a TIMP3 inducer, inhibiting tumor growth, metastasis, and angiogenesis. This compound demonstrates antiproliferative activity against the human colon cancer cell line HCT116 with a GI50 of 0.03 μM.
- Potent HDAC inhibitory ability
- TIMP3 inducer
- Inhibits tumor growth, metastasis, and angiogenesis
- Antiproliferative activity against human colon cancer cell line HCT116
- Molecular weight: 375.40
- Appearance: Solid
- Color: Off-white to light yellow
- Shipping at room temperature in continental US
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
- Solubility (In Vitro): DMSO at 250 mg/mL (665.96 mM)